Statins Impair CD1d-Mediated Antigen Presentation through the Inhibition of Prenylation
نویسندگان
چکیده
منابع مشابه
Statins impair CD1d-mediated antigen presentation through the inhibition of prenylation.
Statins are widely used as cholesterol-lowering agents that also decrease inflammation and target enzymes essential for prenylation, an important process in the activation and intracellular transport of proteins vital for a wide variety of cellular functions. Here, we report that statins impair a critical component of the innate immune response, CD1d-mediated Ag presentation. The addition of sp...
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ژورنال
عنوان ژورنال: The Journal of Immunology
سال: 2009
ISSN: 0022-1767,1550-6606
DOI: 10.4049/jimmunol.0804311